Rat glutamate receptor, ionotropic, N-methyl D-aspartate 2C ELISA Kit | GRIN2C elisa kit

Rat Glutamate [NMDA] receptor subunit epsilon-3, GRIN2C ELISA Kit

Cat. Num. AAA9340550

• Gene Names: Grin2c; NR2C; GluN2C
• Reactivity: Rat
• Synonyms: glutamate receptor; ionotropic; N-methyl D-aspartate 2C; Rat Glutamate [NMDA] receptor subunit epsilon-3; GRIN2C ELISA Kit; Rat Glutamate [NMDA] receptor subunit epsilon-3 (GRIN2C) ELISA kit; NMDAR2C; NR2C; N-methyl-D-aspartate receptor subunit 2C; GRIN2C elisa kit

• Reactivity: Rat
• Specificity: No significant cross-reactivity or interference between Rat GRIN2C and analogues was observed.

• Samples: Serum, Plasma, Tissue Homogenate, Feces and Urine
• Assay Type: Sandwich
• Detection Range: 31.2 pg/ml - 1000 pg/ml.
• Sensitivity: 5.0 pg/ml.
• Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic applications! It is intended to be determinated GRIN2C concentrations in Rat serum, plasma and other body fluids. Using Purified Rat GRIN2C antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add GRIN2C and GRIN2C antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of GRIN2C in the samples is then determined by comparing the O.D. of the samples to the standard curve.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for GRIN2C elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! It is intended to be determinated GRIN2C concentrations in Rat serum, plasma and other body fluids. Using Purified Rat GRIN2C antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add GRIN2C and GRIN2C antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of GRIN2C in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 148747563
• NCBI GeneID: 24411
• NCBI Accession #: NP_036707.3
• NCBI GenBank Nucleotide #: NM_012575.3
• UniProt Accession #: Q00961
• Molecular Weight: 135,271 Da
• NCBI Official Full Name: glutamate receptor ionotropic, NMDA 2C
• NCBI Official Synonym Full Names: glutamate receptor, ionotropic, N-methyl D-aspartate 2C
• NCBI Official Symbol: Grin2c
• NCBI Official Synonym Symbols: NR2C; GluN2C
• NCBI Protein Information: glutamate receptor ionotropic, NMDA 2C; NMDAR2C; NMDA glutamate receptor; glutamate receptor, ionotropic, NMDA2C; N-methyl D-aspartate receptor subtype 2C; glutamate [NMDA] receptor subunit epsilon-3
• UniProt Protein Name: Glutamate receptor ionotropic, NMDA 2C
• Protein Family: Glutamate receptor ionotropic
• UniProt Gene Name: Grin2c
• UniProt Synonym Gene Names: GluN2C; NMDAR2C; NR2C
• UniProt Entry Name: NMDE3_RAT

NCBI Description

subunit that in combination with NMDAR1 displays NMDA receptor activity; may contribute to NMDA receptor functional diversity [RGD, Feb 2006]

Uniprot Description

NMDAR2C: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2C/GRIN2C subfamily.

Protein type: Membrane protein, integral; Channel, calcium; Channel, ligand-gated; Membrane protein, multi-pass

Cellular Component: postsynaptic membrane; postsynaptic density; dendrite; cell junction; N-methyl-D-aspartate selective glutamate receptor complex

Molecular Function: protein binding; extracellular-glutamate-gated ion channel activity; ionotropic glutamate receptor activity; N-methyl-D-aspartate selective glutamate receptor activity; protein N-terminus binding; cation channel activity; PDZ domain binding

Biological Process: synaptic transmission, glutamatergic; protein localization; regulation of membrane potential; startle response; ionotropic glutamate receptor signaling pathway; directional locomotion; response to wounding; neuromuscular process controlling balance; negative regulation of protein catabolic process; regulation of excitatory postsynaptic membrane potential