Mouse solute carrier family 22 (organic cation transporter) , member 2 ELISA Kit | SLC22A2 elisa kit
Mouse Solute carrier family 22 member 2, SLC22A2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SLC22A2: Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamin, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, SLC family
Cellular Component: membrane; basolateral plasma membrane; integral to plasma membrane; integral to membrane
Molecular Function: transporter activity; ion transmembrane transporter activity; organic cation transmembrane transporter activity; transmembrane transporter activity; quaternary ammonium group transmembrane transporter activity; steroid binding; choline transmembrane transporter activity
Biological Process: histamine transport; organic cation transport; quaternary ammonium group transport; transport; ion transport; choline transport; transmembrane transport; cation transport
Research Articles on SLC22A2
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Product Notes
The Mouse SLC22A2 slc22a2 (Catalog #AAA9340466) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9340466 ELISA Kit recognizes Mouse SLC22A2. It is sometimes possible for the material contained within the vial of "solute carrier family 22 (organic cation transporter) , member 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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