Human guanylate cyclase 1, soluble, alpha 2 ELISA Kit | GUCY1A2 elisa kit
Human Guanylate cyclase soluble subunit alpha-2, GUCY1A2 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Uniprot Description
GUCY1A2: Has guanylyl cyclase on binding to the beta-1 subunit. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 4.6.1.2; Lyase; Nucleotide Metabolism - purine; Guanylyl cyclase
Chromosomal Location of Human Ortholog: 11q21-q22
Cellular Component: cytoplasm
Molecular Function: guanylate cyclase activity; GTP binding; heme binding
Biological Process: cGMP biosynthetic process; positive regulation of cGMP biosynthetic process; signal transduction; blood coagulation
Research Articles on GUCY1A2
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Product Notes
The Human GUCY1A2 gucy1a2 (Catalog #AAA9340352) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9340352 ELISA Kit recognizes Human GUCY1A2. It is sometimes possible for the material contained within the vial of "guanylate cyclase 1, soluble, alpha 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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