Human immature colon carcinoma transcript 1 ELISA Kit | ICT1 elisa kit
Human Peptidyl-tRNA hydrolase ICT1, mitochondrial, ICT1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. Deviation from the normal maturation pathway by neoplastic transformation is thought to initiate in stem cells or their early descendants. One potential marker is ICT1 whose mRNA and protein were more highly expressed in undifferentiated than in differentiated cells. [provided by RefSeq, Jul 2008]
Uniprot Description
ICT1: Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. Belongs to the prokaryotic/mitochondrial release factor family. ICT1 subfamily.
Protein type: Mitochondrial; EC 3.1.1.29
Chromosomal Location of Human Ortholog: 17q25.1
Cellular Component: mitochondrion; mitochondrial matrix; mitochondrial inner membrane; mitochondrial large ribosomal subunit
Molecular Function: aminoacyl-tRNA hydrolase activity; translation release factor activity, codon nonspecific
Biological Process: mitochondrial translation; organelle organization and biogenesis
Research Articles on ICT1
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Product Notes
The Human ICT1 ict1 (Catalog #AAA9339700) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9339700 ELISA Kit recognizes Human ICT1. It is sometimes possible for the material contained within the vial of "immature colon carcinoma transcript 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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