Rat RAP1B, member of RAS oncogene family ELISA Kit | RAP1B elisa kit
Rat Ras-related protein Rap-1b, RAP1B ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
small GTPase; involved in antagonizing the mitogenic and transforming activity of Ras [RGD, Feb 2006]
Uniprot Description
RAP1B: GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Heterodimer with RAP1GAP. Interacts with EPAC2, SGSM1, SGSM2 and SGSM3. Activated by binding to the GTPase-activating protein RAP1GAP. Activated by guanine nucleotide-exchange factor (GEF) EPAC2 in a cAMP-dependent manner. Belongs to the small GTPase superfamily. Ras family.
Protein type: G protein; G protein, monomeric, Ras; G protein, monomeric
Cellular Component: plasma membrane; lipid particle; intracellular; intercellular junction; cytosol; lipid raft
Molecular Function: GTPase activity; GDP binding; GTP binding; protein complex binding
Biological Process: microvillus biogenesis; cell proliferation; negative regulation of calcium ion-dependent exocytosis; metabolic process; small GTPase mediated signal transduction; Rap protein signal transduction
Research Articles on RAP1B
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Product Notes
The Rat RAP1B rap1b (Catalog #AAA9339203) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9339203 ELISA Kit recognizes Rat RAP1B. It is sometimes possible for the material contained within the vial of "RAP1B, member of RAS oncogene family, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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