Human sperm associated antigen 6 ELISA Kit | SPAG6 elisa kit
Human Sperm-associated antigen 6, SPAG6 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Uniprot Description
SPAG6: Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Cancer Testis Antigen (CTA); Cell development/differentiation
Chromosomal Location of Human Ortholog: 10p12.2
Cellular Component: microtubule cytoskeleton; microtubule; axoneme; nucleus
Biological Process: cell projection organization and biogenesis; spermatid development
Research Articles on SPAG6
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Product Notes
The Human SPAG6 spag6 (Catalog #AAA9337314) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337314 ELISA Kit recognizes Human SPAG6. It is sometimes possible for the material contained within the vial of "sperm associated antigen 6, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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