Rat poly (A) binding protein, cytoplasmic 1 ELISA Kit | PABPC1 elisa kit
Rat Polyadenylate-binding protein 1, PABPC1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
binds with high affinity to poly(A) tails of mRNAs and may be involved in mRNA stabilization and stimulation of translational initiation [RGD, Feb 2006]
Uniprot Description
PABP 1: poly(A) binding protein 1. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Shuttles between the cytoplasm and the nucleus. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. A potential substrate in MAPKAP kinase 2-induced mRNA stabilization. Two alternatively spliced isoforms have been described.
Protein type: Spliceosome; RNA splicing; Motility/polarity/chemotaxis; RNA-binding; Translation
Cellular Component: spliceosome; focal adhesion; membrane; stress granule; cytoplasm; nucleus; ribonucleoprotein complex
Molecular Function: mRNA binding; protein C-terminus binding; protein binding; nucleotide binding; poly(U) binding; poly(A) binding
Biological Process: RNA splicing; mRNA catabolic process, nonsense-mediated decay; RNA-mediated gene silencing; mRNA processing
Research Articles on PABPC1
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Product Notes
The Rat PABPC1 pabpc1 (Catalog #AAA9336907) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9336907 ELISA Kit recognizes Rat PABPC1. It is sometimes possible for the material contained within the vial of "poly (A) binding protein, cytoplasmic 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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