Human guanylate cyclase 2F, retinal ELISA Kit | GUCY2F elisa kit
Human Retinal guanylyl cyclase 2, GUCY2F ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa. [provided by RefSeq, Dec 2008]
Uniprot Description
GUCY2F: Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Protein type: Lyase; Guanylyl cyclase; Membrane protein, integral; Kinase, protein; EC 4.6.1.2; Nucleotide Metabolism - purine; Protein kinase, dual-specificity (receptor); Protein kinase, RGC; Receptor, misc.; RGC group; RGC family
Chromosomal Location of Human Ortholog: Xq22
Cellular Component: nuclear outer membrane; integral to plasma membrane
Molecular Function: guanylate cyclase activity; protein homodimerization activity; GTP binding; protein heterodimerization activity; receptor activity; ATP binding; protein kinase activity
Biological Process: rhodopsin mediated signaling; cGMP biosynthetic process; phototransduction, visible light; regulation of rhodopsin mediated signaling; visual perception; receptor guanylyl cyclase signaling pathway; protein amino acid phosphorylation
Research Articles on GUCY2F
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Product Notes
The Human GUCY2F gucy2f (Catalog #AAA9336449) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9336449 ELISA Kit recognizes Human GUCY2F. It is sometimes possible for the material contained within the vial of "guanylate cyclase 2F, retinal, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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