Mouse cholinergic receptor, nicotinic, alpha 2 (neuronal) ELISA Kit | CHRNA2 elisa kit
Mouse Neuronal acetylcholine receptor subunit alpha-2, CHRNA2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
nAChRA2: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in CHRNA2 are the cause of nocturnal frontal lobe epilepsy type 4 (ENFL4). ENFL4 is an autosomal dominant epilepsy characterized by nocturnal seizures associated with fear sensation, tongue movements, and nocturnal wandering, closely resembling nightmares and sleep walking. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha- 2/CHRNA2 sub-subfamily.
Protein type: Channel, cation; Receptor, misc.; Membrane protein, integral; Channel, ligand-gated; Membrane protein, multi-pass
Cellular Component: nicotinic acetylcholine-gated receptor-channel complex; postsynaptic membrane; membrane; plasma membrane; integral to membrane; synapse; cell junction
Molecular Function: acetylcholine receptor activity; ion channel activity; drug binding; acetylcholine binding; nicotinic acetylcholine-activated cation-selective channel activity; extracellular ligand-gated ion channel activity
Biological Process: synaptic transmission; protein heterooligomerization; transport; ion transport; signal transduction; cation transport
Research Articles on CHRNA2
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Product Notes
The Mouse CHRNA2 chrna2 (Catalog #AAA9335602) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9335602 ELISA Kit recognizes Mouse CHRNA2. It is sometimes possible for the material contained within the vial of "cholinergic receptor, nicotinic, alpha 2 (neuronal), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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