Chicken eyes absent homolog 4 (Drosophila) ELISA Kit | EYA4 elisa kit
Chicken Eyes absent homolog 4, EYA4 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Function: Tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. May be involved in development of the eye
Catalytic activity: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
Cofactor: Binds 1 Mg2+ ion per subunit
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Product Notes
The Chicken EYA4 eya4 (Catalog #AAA9335566) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9335566 ELISA Kit recognizes Chicken EYA4. It is sometimes possible for the material contained within the vial of "eyes absent homolog 4 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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