Rat solute carrier family 5 (sodium iodide symporter) , member 5 ELISA Kit | SLC5A5 elisa kit

Rat Sodium/iodide cotransporter, SLC5A5 ELISA Kit

Cat. Num. AAA9335274

• Gene Names: Slc5a5; Nis
• Reactivity: Rat
• Synonyms: solute carrier family 5 (sodium iodide symporter); member 5; Rat Sodium/iodide cotransporter; SLC5A5 ELISA Kit; Rat Sodium/iodide cotransporter (SLC5A5) ELISA kit; NIS; TDH1; Na (+) /I (-) cotransporter; SLC5A5 elisa kit

• Reactivity: Rat
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Undiluted original Rat serum, plasma or tissue homogenates samples
• Assay Type: Quantitative Sandwich
• Detection Range: 31.2pg/ml-1000pg/ml
• Sensitivity: 5.0pg/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for SLC5A5 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of SLC5A5 (hereafter termed "analyte") in undiluted original Rat serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 158138505
• NCBI GeneID: 114613
• NCBI Accession #: NP_443215.2
• NCBI GenBank Nucleotide #: NM_052983.2
• UniProt Accession #: Q63008
• Molecular Weight: 65,196 Da
• NCBI Official Full Name: sodium/iodide cotransporter
• NCBI Official Synonym Full Names: solute carrier family 5 (sodium/iodide cotransporter), member 5
• NCBI Official Symbol: Slc5a5
• NCBI Official Synonym Symbols: Nis
• NCBI Protein Information: sodium/iodide cotransporter; Na+/I- symporter; Na(+)/I(-) symporter; Na(+)/I(-)-symporter; sodium-iodide symporter; Na(+)/I(-) cotransporter; solute carrier family 5, member 5; solute carrier family 5 (sodium iodide symporter), member 5
• UniProt Protein Name: Sodium/iodide cotransporter
• Protein Family: Sodium/iodide cotransporter
• UniProt Gene Name: Slc5a5
• UniProt Synonym Gene Names: Nis; Na(+)/I(-) cotransporter; Na(+)/I(-) symporter
• UniProt Entry Name: SC5A5_RAT

NCBI Description

catalyzes Na+/I- symporter activity; plays a role in iodide transport and thyroid hormone generation [RGD, Feb 2006]

Uniprot Description

SLC5A5: Mediates iodide uptake in the thyroid gland. Defects in SLC5A5 are the cause of thyroid dyshormonogenesis 1 (TDH1). A disorder characterized by the inability of the thyroid to maintain a concentration difference of readily exchangeable iodine between the plasma and the thyroid gland, leading to congenital hypothyroidism. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, SLC family

Cellular Component: plasma membrane; integral to membrane; nucleus; vesicle

Molecular Function: iodide transmembrane transporter activity; sodium:iodide symporter activity; symporter activity

Biological Process: iodide transport; sodium ion transport; thyroid hormone generation; anion transport