Mouse UDP-galactose-4-epimerase ELISA Kit | GALE elisa kit
Mouse UDP-glucose 4-epimerase, GALE ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
GALE: Catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. Defects in GALE are the cause of epimerase-deficiency galactosemia (EDG); also known as galactosemia type 3. Clinical features include early-onset cataracts, liver damage, deafness and mental retardation. There are two clinically distinct forms of EDG. (1) A benign, or 'peripheral' form with no detectable GALE activity in red blood cells and characterized by mild symptoms. Some patients may suffer no symptoms beyond raised levels of galactose-1-phosphate in the blood. (2) A much rarer 'generalized' form with undetectable levels of GALE activity in all tissues and resulting in severe features such as restricted growth and mental development. Belongs to the sugar epimerase family.
Protein type: Carbohydrate Metabolism - galactose; Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC 5.1.3.7; EC 5.1.3.2; Isomerase
Molecular Function: UDP-N-acetylglucosamine 4-epimerase activity; protein homodimerization activity; racemase and epimerase activity, acting on carbohydrates and derivatives; isomerase activity; UDP-glucose 4-epimerase activity; coenzyme binding; catalytic activity
Biological Process: galactose catabolic process; carbohydrate metabolic process; galactose metabolic process
Research Articles on GALE
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Product Notes
The Mouse GALE gale (Catalog #AAA9334779) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9334779 ELISA Kit recognizes Mouse GALE. It is sometimes possible for the material contained within the vial of "UDP-galactose-4-epimerase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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