Human egf-like module containing, mucin-like, hormone receptor-like 2 ELISA Kit | EMR2 elisa kit

Human EGF-like module-containing mucin-like hormone receptor-like 2, EMR2 ELISA Kit

Cat. Num. AAA9333335

• Gene Names: EMR2; CD312
• Reactivity: Human
• Synonyms: egf-like module containing; mucin-like; hormone receptor-like 2; Human EGF-like module-containing mucin-like hormone receptor-like 2; EMR2 ELISA Kit; Human EGF-like module-containing mucin-like hormone receptor-like 2 (EMR2) ELISA kit; CD312; DKFZp781B135; hormone receptor-like sequence 2; EMR2 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Body fluids, tissue homogenates, secretions or feces samples
• Assay Type: Quantitative Sandwich
• Detection Range: 3.12ng/ml-100ng/ml
• Sensitivity: 1.0ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for EMR2 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of EMR2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 402743849
• NCBI GeneID: 30817
• NCBI Accession #: NP_001257981.1
• NCBI GenBank Nucleotide #: NM_001271052.1
• UniProt Accession #: Q9UHX3; Q8NG96; Q9Y4B1; B4DQ96; E7ESD7; E9PBR1; E9PEL6; E9PFQ5; E9PG91
• Molecular Weight: 90,472 Da
• NCBI Official Full Name: EGF-like module-containing mucin-like hormone receptor-like 2 isoform h
• NCBI Official Synonym Full Names: egf-like module containing, mucin-like, hormone receptor-like 2
• NCBI Official Symbol: EMR2
• NCBI Official Synonym Symbols: CD312
• NCBI Protein Information: EGF-like module-containing mucin-like hormone receptor-like 2
• UniProt Protein Name: EGF-like module-containing mucin-like hormone receptor-like 2
• UniProt Gene Name: EMR2
• UniProt Entry Name: EMR2_HUMAN

NCBI Description

This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

Uniprot Description

EMR2: Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 2

Chromosomal Location of Human Ortholog: 19p13.1

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; calcium ion binding

Biological Process: G-protein coupled receptor protein signaling pathway; cell migration; cell adhesion; inflammatory response