Mouse ubiquitin specific peptidase 9, X-linked ELISA Kit | USP9X elisa kit
Mouse Probable ubiquitin carboxyl-terminal hydrolase FAF-X, USP9X ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
USP9X: Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important role regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Interacts with SMAD4, MARK4, NUAK1 and BIRC5/survivin. Widely expressed in embryonic and adult tissues. Belongs to the peptidase C19 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin-specific protease; Protease; EC 3.4.19.12; Ubiquitin conjugating system
Cellular Component: cell projection; growth cone; membrane; apical part of cell; cytoplasm
Molecular Function: peptidase activity; protein binding; hydrolase activity; cysteine-type endopeptidase activity; ubiquitin-specific protease activity; cysteine-type peptidase activity
Biological Process: ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-dependent protein catabolic process; mitosis; protein deubiquitination; in utero embryonic development; axon extension; hippocampus development; neuron migration; proteolysis; cell cycle; cerebellar cortex structural organization; chromosome segregation; post-embryonic development; BMP signaling pathway; cell division; transforming growth factor beta receptor signaling pathway
Research Articles on USP9X
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Product Notes
The Mouse USP9X usp9x (Catalog #AAA9331359) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9331359 ELISA Kit recognizes Mouse USP9X. It is sometimes possible for the material contained within the vial of "ubiquitin specific peptidase 9, X-linked, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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