Human myosin, heavy chain 14 ELISA Kit | MYH14 elisa kit
Human Myosin-14, MYH14 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-14 (MYO14). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Uniprot Description
MYH14: Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). High levels of expression are found in small intestine, colon and skeletal muscle. Expression is low in organs composed mainly of smooth muscle, such as aorta, uterus and urinary bladder. No detectable expression is found in thymus, spleen, placenta and lymphocytes. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Motor
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: growth cone; membrane; myosin II complex; axon; cytoplasm; stress fiber; actomyosin
Molecular Function: calmodulin binding; actin filament binding; microfilament motor activity; actin-dependent ATPase activity; ATP binding
Biological Process: skeletal muscle contraction; axon guidance; regulation of cell shape; skeletal muscle development; sensory perception of sound; actin filament-based movement; metabolic process; actomyosin structure organization and biogenesis; ephrin receptor signaling pathway; generation of action potential
Disease: Peripheral Neuropathy, Myopathy, Hoarseness, And Hearing Loss; Deafness, Autosomal Dominant 4a
Research Articles on MYH14
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Product Notes
The Human MYH14 myh14 (Catalog #AAA9330001) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9330001 ELISA Kit recognizes Human MYH14. It is sometimes possible for the material contained within the vial of "myosin, heavy chain 14, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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