Human REV1 homolog (S. cerevisiae) ELISA Kit | REV1 elisa kit
Human DNA repair protein REV1, REV1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found. [provided by RefSeq, Jul 2008]
Uniprot Description
REV1L: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. Belongs to the DNA polymerase type-Y family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.7.7.-; DNA repair, damage; Transferase
Chromosomal Location of Human Ortholog: 2q11.1-q11.2
Cellular Component: nucleoplasm
Molecular Function: protein binding; magnesium ion binding; DNA-directed DNA polymerase activity; damaged DNA binding; deoxycytidyl transferase activity
Biological Process: error-prone postreplication DNA repair; DNA repair; DNA replication; response to UV
Research Articles on REV1
Similar Products
Product Notes
The Human REV1 rev1 (Catalog #AAA9329843) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9329843 ELISA Kit recognizes Human REV1. It is sometimes possible for the material contained within the vial of "REV1 homolog (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
