Rat mitogen-activated protein kinase kinase 5 ELISA Kit | MAP2K5 elisa kit

Rat Dual specificity mitogen-activated protein kinase kinase 5, MAP2K5 ELISA Kit

Cat. Num. AAA9329832

• Gene Names: Map2k5; Mek5
• Reactivity: Rat
• Synonyms: mitogen-activated protein kinase kinase 5; Rat Dual specificity mitogen-activated protein kinase kinase 5; MAP2K5 ELISA Kit; Rat Dual specificity mitogen-activated protein kinase kinase 5 (MAP2K5) ELISA kit; HsT17454; MAPKK5; MEK5; PRKMK5; MAP kinase kinase MEK5b; MAPK/ERK kinase 5; dual specificity mitogen-activated protein kinase kinase 5; MAP2K5 elisa kit

• Reactivity: Rat

• Samples: Human Body Fluids And Tissue Homogenates
• Assay Type: Quantitative Sandwich
• Detection Range: 0.25ng/ml-8ng/ml
• Sensitivity: 0.1ng/ml.
• Intra-assay Precision: Intra-assay CV (%) are less than 15%
• Inter-assay Precision: Inter-assay CV (?) are less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for MAP2K5 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only! This kit is intended to be used for determine the level of MAP2K3 (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 77157802
• NCBI GeneID: 29568
• NCBI Accession #: NP_001029159.1
• NCBI GenBank Nucleotide #: NM_001033987.1
• UniProt Accession #: Q62862; Q62863; Q62864
• Molecular Weight: 50,198 Da
• NCBI Official Full Name: dual specificity mitogen-activated protein kinase kinase 5 isoform a
• NCBI Official Synonym Full Names: mitogen activated protein kinase kinase 5
• NCBI Official Symbol: Map2k5
• NCBI Official Synonym Symbols: Mek5
• NCBI Protein Information: dual specificity mitogen-activated protein kinase kinase 5; MEK 5; MAPKK 5; MAPK/ERK kinase 5; MAP kinase kinase 5
• UniProt Protein Name: Dual specificity mitogen-activated protein kinase kinase 5
• Protein Family: Mitogen-activated protein kinase kinase
• UniProt Gene Name: Map2k5
• UniProt Synonym Gene Names: Mek5; Mkk5; Prkmk5; MAP kinase kinase 5; MAPKK 5; MEK 5
• UniProt Entry Name: MP2K5_RAT

NCBI Description

kinase involved in signal transduction in the cell [RGD, Feb 2006]

Uniprot Description

MEK5: a dual specificity protein kinase of the STE7 family. Activates ERK5 and is itself phosphorylated and activated by MEKK3, as well as by atypical protein kinase C isoforms. Involved in growth factor stimulated cell proliferation and muscle cell differentiation. Four alternatively spliced isoforms have been described.

Protein type: Kinase, protein; Protein kinase, dual-specificity (non-receptor); Protein kinase, STE; EC 2.7.12.2; STE group; STE7 family

Cellular Component: membrane; spindle; intracellular; nucleus; cytosol

Molecular Function: MAP kinase kinase activity; protein serine/threonine kinase activity; protein-tyrosine kinase activity; metal ion binding; ATP binding; protein kinase activity

Biological Process: peptidyl-tyrosine phosphorylation; negative regulation of heterotypic cell-cell adhesion; activation of MAPK activity; heart development; negative regulation of interleukin-8 biosynthetic process; MAPKKK cascade; negative regulation of caspase activity; negative regulation of transcription from RNA polymerase II promoter; positive regulation of cell growth; positive regulation of protein metabolic process; protein amino acid phosphorylation; inhibition of NF-kappaB transcription factor; positive regulation of transcription from RNA polymerase II promoter; positive regulation of epithelial cell proliferation