Human phospholipase D family, member 6 ELISA Kit | PLD6 elisa kit
Human Mitochondrial cardiolipin hydrolase, PLD6 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PLD6: Cardiolipin hydrolase present at the mitochondrial outer membrane required both for mitochondrial fusion and piRNA metabolic process. Acts by catalyzing the hydrolysis of cardiolipin (diphosphatidylglycerol) to form phosphatidate (phosphatidic acid or PA) at the mitochondrial outer membrane surface, promoting mitochondrial fusion. The production of phosphatidate also regulates the piRNA metabolic process by promoting recruitment and/or activation of components of the meiotic nuage, also named P granule, a critical step for primary biogenesis of piRNAs. Required during spermatogenesis to repress transposable elements and prevent their mobilization via its role in the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Belongs to the phospholipase D family. MitoPLD/Zucchini subfamily.
Protein type: Phospholipase; Membrane protein, integral; EC 3.1.4.-; EC 3.1.4.4
Chromosomal Location of Human Ortholog: 17p11.2
Cellular Component: mitochondrial outer membrane; integral to membrane
Molecular Function: protein homodimerization activity; endonuclease activity; metal ion binding
Biological Process: meiosis; polar granule organization and biogenesis; mitochondrial fusion; phosphatidylglycerol biosynthetic process; phospholipid metabolic process; DNA methylation during gametogenesis; glycerophospholipid biosynthetic process; gene expression; lipid catabolic process; spermatid development
Research Articles on PLD6
Similar Products
Product Notes
The Human PLD6 pld6 (Catalog #AAA9329492) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9329492 ELISA Kit recognizes Human PLD6. It is sometimes possible for the material contained within the vial of "phospholipase D family, member 6, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
