Human receptor (G protein-coupled) activity modifying protein 3 ELISA Kit | RAMP3 elisa kit
Human Receptor activity-modifying protein 3, RAMP3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor. [provided by RefSeq, Jul 2008]
Uniprot Description
RAMP3: Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL. Belongs to the RAMP family.
Protein type: Receptor, misc.; Membrane protein, integral
Chromosomal Location of Human Ortholog: 7p13-p12
Cellular Component: cell surface; integral to plasma membrane; lysosome; plasma membrane; intracellular; receptor complex
Molecular Function: protein binding; coreceptor activity; receptor activity; protein transporter activity
Biological Process: intracellular protein transport; protein transport; receptor internalization; calcium ion transport; negative regulation of transcription, DNA-dependent; positive regulation of receptor recycling; regulation of G-protein coupled receptor protein signaling pathway
Research Articles on RAMP3
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Product Notes
The Human RAMP3 ramp3 (Catalog #AAA9329286) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9329286 ELISA Kit recognizes Human RAMP3. It is sometimes possible for the material contained within the vial of "receptor (G protein-coupled) activity modifying protein 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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