Human SUMO1/sentrin specific peptidase 7 ELISA Kit | SENP7 elisa kit
Human Sentrin-specific protease 7, SENP7 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009]
Uniprot Description
SENP7: Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full- length SUMO proteins to their mature forms. Belongs to the peptidase C48 family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.22.68; Protease
Chromosomal Location of Human Ortholog: 3q12
Cellular Component: intracellular; nucleus
Molecular Function: protein binding; cysteine-type peptidase activity
Biological Process: proteolysis
Research Articles on SENP7
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Product Notes
The Human SENP7 senp7 (Catalog #AAA9328678) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9328678 ELISA Kit recognizes Human SENP7. It is sometimes possible for the material contained within the vial of "SUMO1/sentrin specific peptidase 7, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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