Rat aldo-keto reductase family 1, member A1 (aldehyde reductase) ELISA Kit | AKR1A1 elisa kit
Rat Alcohol dehydrogenase [NADP+], AKR1A1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
enzyme that catalyzes the NADPH-dependent reduction of 3-deoxyglucosone; important for detoxifying 3-deoxyglucosone when it is formed through the Maillard reaction in vivo [RGD, Feb 2006]
Uniprot Description
AKR1A1: Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4- nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D- glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN). Belongs to the aldo/keto reductase family.
Protein type: EC 1.1.1.2; Lipid Metabolism - glycerolipid; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Oxidoreductase
Cellular Component: extracellular space; apical plasma membrane; cytosol
Molecular Function: L-glucuronate reductase activity; aldehyde reductase activity; alcohol dehydrogenase (NADP+) activity
Biological Process: L-ascorbic acid biosynthetic process; aldehyde catabolic process; D-glucuronate catabolic process
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Product Notes
The Rat AKR1A1 akr1a1 (Catalog #AAA9328466) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9328466 ELISA Kit recognizes Rat AKR1A1. It is sometimes possible for the material contained within the vial of "aldo-keto reductase family 1, member A1 (aldehyde reductase), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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