Human E2F transcription factor 7 ELISA Kit | E2F7 elisa kit
Human Transcription factor E2F7, E2F7 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
E2F transcription factors, such as E2F7, play an essential role in the regulation of cell cycle progression (Di Stefano et al., 2003 [PubMed 14633988]).[supplied by OMIM, May 2008]
Uniprot Description
E2F7: Along with E2F8, inhibitor of E2F-dependent transcription that is important for the control of the E2F1-TP53 apoptotic pathway. Directly represses E2F1 transcription. Binds DNA independently of DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Appears to regulate a subset of E2F-dependent genes whose products are required for normal cell cycle progession. Belongs to the E2F/DP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor; Cell cycle regulation; DNA-binding
Chromosomal Location of Human Ortholog: 12q21.2
Cellular Component: transcription factor complex; nucleus
Molecular Function: identical protein binding; protein binding; transcription corepressor activity; transcription factor activity
Biological Process: negative regulation of cell proliferation; DNA damage response, signal transduction by p53 class mediator; transcription, DNA-dependent; positive regulation of DNA endoreduplication; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; sprouting angiogenesis; negative regulation of cytokinesis; placenta development
Research Articles on E2F7
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Product Notes
The Human E2F7 e2f7 (Catalog #AAA9327892) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9327892 ELISA Kit recognizes Human E2F7. It is sometimes possible for the material contained within the vial of "E2F transcription factor 7, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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