Rat dopamine receptor D5 ELISA Kit | DRD5 elisa kit
Rat D (1B) dopamine receptor, DRD5 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
dopamine receptor; may play a role in stimulation of adenylyl cyclase, activation of phospholipase C, and phosphatidylinositol phosphate metabolism in the central nervous system [RGD, Feb 2006]
Uniprot Description
DRD5: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. Defects in DRD5 are a cause of benign essential blepharospasm (BEB). BEB is a primary focal dystonia affecting the orbicularis oculi muscles. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. BEB usually begins in middle age. Initial symptoms include eye irritation and frequent blinking, progressing to involuntary spasms of eyelid closure. Patients have normal eyes. The visual disturbance is due solely to the forced closure of the eyelids. In severe cases, this can lead to functional blindness. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1
Cellular Component: cell soma; integral to plasma membrane; axon; brush border membrane; dendrite; plasma membrane; dendritic spine
Molecular Function: protein binding; dopamine receptor activity; dopamine binding; G-protein alpha-subunit binding; drug binding; dopamine D1 receptor-like receptor activity
Biological Process: regulation of long-term neuronal synaptic plasticity; synaptic transmission, dopaminergic; wound healing; response to amphetamine; mating behavior; transmission of nerve impulse; norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure; response to cocaine; G-protein signaling, adenylate cyclase activating pathway; synaptic transmission; regulation of female receptivity; regulation of systemic arterial blood pressure by vasopressin; sensitization; positive regulation of cAMP biosynthetic process; dopamine receptor signaling pathway; visual learning; negative regulation of protein kinase activity; positive regulation of adenylate cyclase activity; negative regulation of blood pressure; negative regulation of NAD(P)H oxidase activity; negative regulation of cell migration; associative learning; dopamine receptor, adenylate cyclase activating pathway
Research Articles on DRD5
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Product Notes
The Rat DRD5 drd5 (Catalog #AAA9327850) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9327850 ELISA Kit recognizes Rat DRD5. It is sometimes possible for the material contained within the vial of "dopamine receptor D5, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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