Mouse ubiquitin specific peptidase 4 (proto-oncogene) ELISA Kit | USP4 elisa kit
Mouse Ubiquitin carboxyl-terminal hydrolase 4, USP4 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
USP4: Hydrolase that deubiquitinates target proteins such as the receptor ADORA2A, PDPK1 and TRIM21. Deubiquitination of ADORA2A increases the amount of functional receptor at the cell surface. Plays a role in the regulation of quality control in the ER. Interacts with RB1 (both dephosphorylated and hypophosphorylated forms). Interacts with ADORA2A (via cytoplasmic C-terminus); the interaction is direct. Interacts with RB1, RBL1 and RBL2. Overexpressed in small cell tumors and adenocarcinomas of the lung compared to wild-type lung. Expressed in the hippocampal neurons. Belongs to the peptidase C19 family. USP4 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Oncoprotein; Ubiquitin conjugating system; Protease; EC 3.4.19.12; Ubiquitin-specific protease
Cellular Component: cytoplasm; plasma membrane; nucleus
Molecular Function: peptidase activity; identical protein binding; protein binding; hydrolase activity; metal ion binding; cysteine-type endopeptidase activity; ubiquitin-specific protease activity; adenosine receptor binding; cysteine-type peptidase activity
Biological Process: assembly of spliceosomal tri-snRNP; ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-dependent protein catabolic process; protein deubiquitination; regulation of protein stability; negative regulation of protein ubiquitination; proteolysis
Research Articles on USP4
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Product Notes
The Mouse USP4 usp4 (Catalog #AAA9327404) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9327404 ELISA Kit recognizes Mouse USP4. It is sometimes possible for the material contained within the vial of "ubiquitin specific peptidase 4 (proto-oncogene), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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