Human growth arrest-specific 2 ELISA Kit | GAS2 elisa kit

Human Growth arrest-specific protein 2, GAS2 ELISA Kit

Cat. Num. AAA9326632

• Reactivity: Human
• Synonyms: growth arrest-specific 2; Human Growth arrest-specific protein 2; GAS2 ELISA Kit; Human Growth arrest-specific protein 2 (GAS2) ELISA kit; MGC32610; ; GAS2 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Assay Type: Quantitative Sandwich
• Detection Range: 0.625 ng/ml - 20 ng/ml
• Sensitivity: 0.1 ng/ml
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for GAS2 elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of GAS2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 219842340
• NCBI GeneID: 2620
• NCBI Accession #: NP_001137302.1
• NCBI GenBank Nucleotide #: NM_001143830.1
• UniProt Accession #: O43903; Q6ICV8; Q7Z3X8; B2R9C8; D3DQZ0
• Molecular Weight: 34,945 Da
• NCBI Official Full Name: growth arrest-specific protein 2
• NCBI Official Synonym Full Names: growth arrest-specific 2
• NCBI Official Symbol: GAS2
• NCBI Protein Information: growth arrest-specific protein 2; GAS-2
• UniProt Protein Name: Growth arrest-specific protein 2
• Protein Family: Germacrene A synthase
• UniProt Gene Name: GAS2
• UniProt Synonym Gene Names: GAS-2
• UniProt Entry Name: GAS2_HUMAN

NCBI Description

The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2009]

Uniprot Description

GAS2: May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process. Belongs to the GAS2 family.

Protein type: Motility/polarity/chemotaxis; Apoptosis

Chromosomal Location of Human Ortholog: 11p14.3

Cellular Component: membrane; actin filament; cytosol

Biological Process: regulation of cell shape; apoptosis; cell cycle arrest; cell structure disassembly during apoptosis