Mouse solute carrier family 27 (fatty acid transporter) , member 2 ELISA Kit | SLC27A2 elisa kit
Mouse Very long-chain acyl-CoA synthetase, SLC27A2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
SLC27A2: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7- alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes. Belongs to the ATP-dependent AMP-binding enzyme family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; EC 6.2.1.3; Ligase
Cellular Component: peroxisomal membrane; integral to peroxisomal membrane; endoplasmic reticulum membrane; intracellular membrane-bound organelle; mitochondrion; membrane; endoplasmic reticulum lumen; endoplasmic reticulum; integral to membrane; integral to endoplasmic reticulum membrane; peroxisome
Molecular Function: branched-chain acyl-CoA synthetase (ADP-forming) activity; acyl-CoA ligase activity; fatty acid transporter activity; succinate-CoA ligase activity; nucleotide binding; 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity; 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity; very-long-chain-fatty-acid-CoA ligase activity; phytanate-CoA ligase activity; 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid (OPC-8:0) CoA ligase activity; enzyme binding; fatty-acid ligase activity; benzoyl acetate-CoA ligase activity; 2,4-dichlorobenzoate-CoA ligase activity; aryl-CoA synthetase (ADP-forming) activity; catalytic activity; ATP binding; receptor binding; long-chain-fatty-acid-CoA ligase activity; ligase activity
Biological Process: bile acid biosynthetic process; fatty acid beta-oxidation; very-long-chain fatty acid metabolic process; very-long-chain fatty acid catabolic process; metabolic process; lipid metabolic process; long-chain fatty acid metabolic process; fatty acid metabolic process; fatty acid transport; fatty acid alpha-oxidation
Research Articles on SLC27A2
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Product Notes
The Mouse SLC27A2 slc27a2 (Catalog #AAA9326151) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9326151 ELISA Kit recognizes Mouse SLC27A2. It is sometimes possible for the material contained within the vial of "solute carrier family 27 (fatty acid transporter) , member 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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