Mouse peroxisome proliferator-activated receptor gamma, coactivator 1 beta ELISA Kit | PPARGC1B elisa kit
Mouse Peroxisome proliferator-activated receptor gamma coactivator 1-beta, PPARGC1B ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PGC-1 beta: Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor
Cellular Component: mitochondrion; Srb-mediator complex; nucleus
Molecular Function: protein binding; nucleic acid binding; ligand-dependent nuclear receptor transcription coactivator activity; AF-2 domain binding; RNA binding; nucleotide binding; estrogen receptor binding; transcription factor binding; receptor activator activity
Biological Process: transcription from RNA polymerase II promoter; ossification; estrogen receptor signaling pathway; transcription, DNA-dependent; positive regulation of osteoclast differentiation; positive regulation of transcription, DNA-dependent; actin filament organization; transcription from mitochondrial promoter; regulation of transcription, DNA-dependent; positive regulation of bone resorption; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; negative regulation of transcription, DNA-dependent; positive regulation of phosphorylation
Research Articles on PPARGC1B
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Product Notes
The Mouse PPARGC1B ppargc1b (Catalog #AAA9323257) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9323257 ELISA Kit recognizes Mouse PPARGC1B. It is sometimes possible for the material contained within the vial of "peroxisome proliferator-activated receptor gamma, coactivator 1 beta, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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