Human FAT tumor suppressor homolog 4 (Drosophila) ELISA Kit | FAT4 elisa kit
Human Protocadherin Fat 4, FAT4 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the protocadherin family. This gene may play a role in regulating planar cell polarity (PCP). Studies in mice suggest that loss of PCP signaling may cause cystic kidney disease, and mutations in this gene have been associated with Van Maldergem Syndrome 2. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Mar 2014]
Uniprot Description
FAT4: May function in the regulation of planar cell polarity. Cadherins are cell-cell interaction molecules. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 4q28.1
Cellular Component: apical part of cell; plasma membrane; integral to membrane
Molecular Function: protein binding; calcium ion binding
Biological Process: heart morphogenesis; heterophilic cell adhesion; inner ear receptor stereocilium organization and biogenesis; neurogenesis; gut development; plasma membrane organization and biogenesis; ureteric bud branching; cerebral cortex development; homophilic cell adhesion
Disease: Van Maldergem Syndrome 2; Hennekam Lymphangiectasia-lymphedema Syndrome 2
Research Articles on FAT4
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Product Notes
The Human FAT4 fat4 (Catalog #AAA9322414) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9322414 ELISA Kit recognizes Human FAT4. It is sometimes possible for the material contained within the vial of "FAT tumor suppressor homolog 4 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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