Mouse aldehyde dehydrogenase 5 family, member A1 ELISA Kit | ALDH5A1 elisa kit
Mouse Succinate-semialdehyde dehydrogenase, mitochondrial, ALDH5A1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
ALDH5A1: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). Defects in ALDH5A1 are the cause of succinate semialdehyde dehydrogenase deficiency (SSADH deficiency). SSADH deficiency is a rare inborn error in the metabolism of 4-aminobutyric acid (GABA) which leads to accumulation of 4-hydroxybutyric acid in physiologic fluids of patients. The disease is characterized by severe ataxia and by mildly retarded psychomotor development. Belongs to the aldehyde dehydrogenase family.
Protein type: Amino Acid Metabolism - alanine, aspartate and glutamate; EC 1.2.1.24; Oxidoreductase; Mitochondrial; Carbohydrate Metabolism - butanoate
Cellular Component: mitochondrion
Molecular Function: aldehyde dehydrogenase (NAD) activity; carboxylic acid binding; oxidoreductase activity; succinate-semialdehyde dehydrogenase activity; NAD binding; succinate-semialdehyde dehydrogenase [NAD(P)+] activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
Biological Process: succinate metabolic process; glutamate metabolic process; neurotransmitter catabolic process; central nervous system development; short-chain fatty acid metabolic process; metabolic process; gamma-aminobutyric acid metabolic process; acetate metabolic process; glucose metabolic process; glutamine metabolic process; glucosylceramide metabolic process; post-embryonic development; protein homotetramerization; glutathione metabolic process; galactosylceramide metabolic process; glycerophospholipid metabolic process; gamma-aminobutyric acid catabolic process
Research Articles on ALDH5A1
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Product Notes
The Mouse ALDH5A1 aldh5a1 (Catalog #AAA9318822) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9318822 ELISA Kit recognizes Mouse ALDH5A1. It is sometimes possible for the material contained within the vial of "aldehyde dehydrogenase 5 family, member A1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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