Mouse nth endonuclease III-like 1 (E. coli) ELISA Kit | NTHL1 elisa kit
Mouse Endonuclease III-like protein 1, NTHL1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
NTHL1: Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incises damaged DNA at cytosines, thymines and guanines. Acts on a damaged strand, 5' from the damaged site. Required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions. Belongs to the Nth/MutY family.
Protein type: EC 4.2.99.18; Mitochondrial; DNA repair, damage; Hydrolase; Lyase
Cellular Component: mitochondrion; nucleus
Molecular Function: single-strand selective uracil DNA N-glycosylase activity; DNA-(apurinic or apyrimidinic site) lyase activity; uracil DNA N-glycosylase activity; hydrolase activity; metal ion binding; DNA N-glycosylase activity; iron-sulfur cluster binding; hydrolase activity, acting on glycosyl bonds; lyase activity; purine-specific mismatch base pair DNA N-glycosylase activity; DNA-3-methyladenine glycosylase III activity; DNA binding; 4 iron, 4 sulfur cluster binding; double-stranded DNA binding; catalytic activity
Biological Process: base-excision repair, AP site formation; base-excision repair; metabolic process; DNA repair; DNA catabolic process, endonucleolytic; nucleotide-excision repair, DNA incision, 5'-to lesion; response to DNA damage stimulus
Research Articles on NTHL1
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Product Notes
The Mouse NTHL1 nthl1 (Catalog #AAA9318412) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9318412 ELISA Kit recognizes Mouse NTHL1. It is sometimes possible for the material contained within the vial of "nth endonuclease III-like 1 (E. coli), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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