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Mouse ring finger and CCCH-type zinc finger domains 1 ELISA Kit | RC3H1 elisa kit

Mouse Roquin, RC3H1 ELISA Kit

Gene Names
Rc3h1; Gm551; N28103; mKIAA2025; 5730557L09Rik
Reactivity
Mouse
Synonyms
ring finger and CCCH-type zinc finger domains 1; Mouse Roquin; RC3H1 ELISA Kit; Mouse Roquin (RC3H1) ELISA kit; RP5-1198E17.5; KIAA2025; RNF198; ROQUIN; roquin; RC3H1 elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Preparation and Storage
Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
125,378 Da
NCBI Official Full Name
roquin-1
NCBI Official Synonym Full Names
RING CCCH (C3H) domains 1
NCBI Official Symbol
Rc3h1
NCBI Official Synonym Symbols
Gm551; N28103; mKIAA2025; 5730557L09Rik
NCBI Protein Information
roquin-1; protein Sanroque; RING finger and C3H zinc finger protein 1; probable E3 ubiquitin-protein ligase Roquin; RING finger and CCCH-type zinc finger domain-containing protein 1
UniProt Protein Name
Roquin-1
Protein Family
UniProt Gene Name
Rc3h1
UniProt Synonym Gene Names
Gm551; Kiaa2025; Roquin
UniProt Entry Name
RC3H1_MOUSE

Uniprot Description

RC3H1: Represses ICOS function, an essential costimulatory receptor for follicular T-cells. May act as an ubiquitin ligase that regulates ubiquitin-dependent control of AU-rich mRNAs by AUF1/HNRPD and HUR/ELAVL1. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Ubiquitin conjugating system

Cellular Component: stress granule; cytoplasm

Molecular Function: mRNA binding; protein binding; mRNA 3'-UTR binding; zinc ion binding; RNA binding; metal ion binding

Biological Process: spleen development; negative regulation of germinal center formation; negative regulation of activated T cell proliferation; negative regulation of B cell proliferation; regulation of mRNA stability; lymph node development; regulation of germinal center formation; T cell proliferation; negative regulation of T-helper cell differentiation; B cell homeostasis; regulation of gene expression; regulation of T cell receptor signaling pathway; T cell homeostasis; cytoplasmic mRNA processing body assembly

Research Articles on RC3H1

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Product Notes

The Mouse RC3H1 rc3h1 (Catalog #AAA9318000) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9318000 ELISA Kit recognizes Mouse RC3H1. It is sometimes possible for the material contained within the vial of "ring finger and CCCH-type zinc finger domains 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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