Mouse mitogen-activated protein kinase kinase kinase kinase 4 ELISA Kit | MAP4K4 elisa kit

Mouse Mitogen-activated protein kinase kinase kinase kinase 4, MAP4K4 ELISA Kit

Cat. Num. AAA9317805

• Gene Names: Map4k4; HGK; Nik; AU043147; AU045934; AW046177; 9430080K19Rik
• Reactivity: Mouse
• Synonyms: mitogen-activated protein kinase kinase kinase kinase 4; Mouse Mitogen-activated protein kinase kinase kinase kinase 4; MAP4K4 ELISA Kit; Mouse Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) ELISA kit; FLH21957; FLJ10410; FLJ20373; FLJ90111; HGK; KIAA0687; NIK; HPK/GCK-like kinase; hepatocyte progenitor kinase-like/germinal center kinase-like kinase; MAP4K4 elisa kit

• Reactivity: Mouse
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Serum, Plasma and Tissue Homogenate
• Assay Type: Sandwich
• Detection Range: 0.5 ng/ml - 16 ng/ml.
• Sensitivity: 0.1 ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for MAP4K4 elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of MAP4K4 (hereafter termed this analyte) in undiluted original Mouse serum, plasma and tissue homogenate samples.

NCBI and Uniprot Product Information

• NCBI GI #: 356582264
• NCBI GeneID: 26921
• NCBI Accession #: NP_001239129.1
• NCBI GenBank Nucleotide #: NM_001252200.1
• UniProt Accession #: P97820
• Molecular Weight: 140,602 Da
• NCBI Official Full Name: mitogen-activated protein kinase kinase kinase kinase 4 isoform 1
• NCBI Official Synonym Full Names: mitogen-activated protein kinase kinase kinase kinase 4
• NCBI Official Symbol: Map4k4
• NCBI Official Synonym Symbols: HGK; Nik; AU043147; AU045934; AW046177; 9430080K19Rik
• NCBI Protein Information: mitogen-activated protein kinase kinase kinase kinase 4; MEKKK 4; MEK kinase kinase 4; NCK interacting kinase; nck-interacting kinase; HPK/GCK-like kinase HGK; MAPK/ERK kinase kinase kinase 4; mitogen activated protein kinase kinase kinase kinase 4
• UniProt Protein Name: Mitogen-activated protein kinase kinase kinase kinase 4
• Protein Family: Mitogen-activated protein kinase kinase kinase kinase
• UniProt Gene Name: Map4k4
• UniProt Synonym Gene Names: Nik; MEK kinase kinase 4; MEKKK 4
• UniProt Entry Name: M4K4_MOUSE

Uniprot Description

HGK: a Ser/Thr kinase of the STE20 subfamily. May play a role in the response to environmental stress and cytokines such as TNF-alpha. May interact with the SH3 domain of the adapter proteins Nck. Binds, via its CNH regulatory domain, to the N- terminal region of SPG3A. Upregulated in primary tumors and tumor cell lines. Required for anchorage-independent growth and ras-dependent focus formation in multiple cell lines. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, STE; Kinase, protein; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); STE group; STE20 family; MSN subfamily

Cellular Component: cytoplasm; intracellular

Molecular Function: transferase activity; protein serine/threonine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; ATP binding; receptor signaling protein serine/threonine kinase activity; protein kinase activity

Biological Process: response to stress; regulation of JNK cascade; phosphorylation; protein amino acid phosphorylation