Rat cholinergic receptor, nicotinic, alpha 10 ELISA Kit | CHRNA10 elisa kit
Rat Neuronal acetylcholine receptor subunit alpha-10, CHRNA10 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
alpha10 subunit of the nicotininc acetylcholine receptor (nAChR); may heterodimerize with alpha9 subunit [RGD, Feb 2006]
Uniprot Description
Function: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this leads to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.3 PublicationsManual assertion based on experiment in:Ref.1
Research Articles on CHRNA10
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Product Notes
The Rat CHRNA10 chrna10 (Catalog #AAA9316752) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9316752 ELISA Kit recognizes Rat CHRNA10. It is sometimes possible for the material contained within the vial of "cholinergic receptor, nicotinic, alpha 10, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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