Rat polo-like kinase 1 (Drosophila) ELISA Kit | PLK1 elisa kit
Rat Serine/threonine-protein kinase PLK1, PLK1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
human homolog catalyzes the phosphorylation of a Golgi reassembly stacking protein (GRASP65); may play a role in Golgi apparatus fragmentation and reorganization during mitosis [RGD, Feb 2006]
Uniprot Description
PLK1: a kinase of the PLK family. Contains a polo-box domain (PBD), a specific phosphoserine or phosphothreonine binding domain. Substrates include BRCA2, Myt1, NudC, Cdc25C, cyclin B1, Nlp and other mitotic proteins. Inhibited by ATR. Plays a role in regulation of cytokinesis and coordinating M-phase events.
Protein type: Protein kinase, Other; EC 2.7.11.21; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Other group; PLK family
Cellular Component: microtubule cytoskeleton; kinetochore; spindle pole; centrosome; spindle microtubule; cytoplasm; nucleolus; spindle; spindle midzone; midbody; nucleus
Molecular Function: protein serine/threonine kinase activity; microtubule binding; protein kinase binding; ATP binding; protein kinase activity
Biological Process: mitosis; protein destabilization; mitotic sister chromatid segregation; positive regulation of proteolysis; regulation of mitotic cell cycle; regulation of mitotic metaphase/anaphase transition; negative regulation of cyclin-dependent protein kinase activity; anaphase-promoting complex activation during mitotic cell cycle; protein ubiquitination; negative regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; response to antibiotic; peptidyl-serine phosphorylation; establishment of protein localization; homologous chromosome segregation; cytokinesis after mitosis; centrosome organization and biogenesis; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of ubiquitin-protein ligase activity; regulation of protein binding; mitotic cell cycle spindle assembly checkpoint; female meiosis chromosome segregation; polar body extrusion after meiotic divisions; G2/M transition of mitotic cell cycle; microtubule bundle formation; negative regulation of apoptosis
Research Articles on PLK1
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Product Notes
The Rat PLK1 plk1 (Catalog #AAA9316620) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9316620 ELISA Kit recognizes Rat PLK1. It is sometimes possible for the material contained within the vial of "polo-like kinase 1 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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