Mouse ring finger protein 144B ELISA Kit | RNF144B elisa kit
Mouse E3 ubiquitin-protein ligase RNF144B, RNF144B ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
RNF144B: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death; But, it is not an anti-apoptotic protein per se. Belongs to the RBR family. RNF144 subfamily.
Protein type: Ubiquitin conjugating system; Ubiquitin ligase; EC 6.3.2.-; Ligase; EC 6.3.2.19; Membrane protein, integral
Cellular Component: membrane; mitochondrion; cytoplasm; mitochondrial membrane; integral to membrane
Molecular Function: zinc ion binding; coenzyme F420-2 alpha-glutamyl ligase activity; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity; metal ion binding; ribosomal S6-glutamic acid ligase activity; ubiquitin-protein ligase activity; coenzyme F420-0 gamma-glutamyl ligase activity; ligase activity
Biological Process: apoptosis; protein ubiquitination during ubiquitin-dependent protein catabolic process
Research Articles on RNF144B
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Product Notes
The Mouse RNF144B rnf144b (Catalog #AAA9316147) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9316147 ELISA Kit recognizes Mouse RNF144B. It is sometimes possible for the material contained within the vial of "ring finger protein 144B, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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