Human Rab geranylgeranyltransferase, beta subunit ELISA Kit | RABGGTB elisa kit
Human Geranylgeranyl transferase type-2 subunit beta, RABGGTB ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the beta-subunit of the enzyme Rab geranylgeranyl-transferase (RabGGTase), which belongs to the protein prenyltransferase family. RabGGTase catalyzes the post-translational addition of geranylgeranyl groups to C-terminal cysteine residues of Rab GTPases. Three small nucleolar RNA genes are present in the intronic regions of this gene. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 3. [provided by RefSeq, Jan 2013]
Uniprot Description
RABGGTB: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively. Belongs to the protein prenyltransferase subunit beta family.
Protein type: Transferase; EC 2.5.1.60
Chromosomal Location of Human Ortholog: 1p31
Cellular Component: Rab-protein geranylgeranyltransferase complex
Molecular Function: protein binding; zinc ion binding; Rab GTPase binding; Rab-protein geranylgeranyltransferase activity
Biological Process: protein geranylgeranylation; visual perception; protein modification process
Research Articles on RABGGTB
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Product Notes
The Human RABGGTB rabggtb (Catalog #AAA9316107) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9316107 ELISA Kit recognizes Human RABGGTB. It is sometimes possible for the material contained within the vial of "Rab geranylgeranyltransferase, beta subunit, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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