Mouse Interleukin 8 Receptor Beta (IL8Rb) ELISA Kit | IL8Rb elisa kit
Mouse Interleukin 8 Receptor Beta (IL8Rb) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
IL-8R B: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Receptor, cytokine; Membrane protein, multi-pass
Cellular Component: cell surface; mast cell granule; membrane; integral to membrane; plasma membrane; intracellular; cytosol
Molecular Function: G-protein coupled receptor activity; protein binding; signal transducer activity; interleukin-8 receptor activity; chemokine receptor activity; interleukin-8 binding; C-X-C chemokine receptor activity
Biological Process: neutrophil chemotaxis; neutrophil activation; positive regulation of leukocyte chemotaxis; signal transduction; chemotaxis; positive regulation of vascular permeability; negative regulation of neutrophil apoptosis; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; positive regulation of angiogenesis; cell surface receptor linked signal transduction; receptor internalization; positive regulation of cell proliferation; cellular defense response; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); acute inflammatory response to antigenic stimulus; negative regulation of apoptosis
Research Articles on IL8Rb
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Product Notes
The Mouse IL8Rb cxcr2 (Catalog #AAA9309532) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9309532 ELISA Kit recognizes Mouse IL8Rb. It is sometimes possible for the material contained within the vial of "Interleukin 8 Receptor Beta (IL8Rb), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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