Mouse ATP-sensitive inward rectifier potassium channel 12, KCNJ12/Kir2.2 ELISA Kit | KCNJ12/Kir2.2 elisa kit

Mouse ATP-sensitive inward rectifier potassium channel 12, KCNJ12/Kir2.2 ELISA Kit

Gene Names

KCNJ12; IRK2; hIRK; IRK-2; hIRK1; KCNJN1; Kir2.2; Kir2.2v; kcnj12x; hkir2.2x

Reactivity

Mouse

Synonyms

ATP-sensitive inward rectifier potassium channel 12; KCNJ12/Kir2.2; Mouse ATP-sensitive inward rectifier potassium channel 12; KCNJ12/Kir2.2 ELISA Kit; KCNJ12/Kir2.2 elisa kit

Ordering
Cat. Num. AAA9306729 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Mouse

Preparation and Storage

Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

NCBI GI #

23110982

NCBI GeneID

3768

NCBI Accession #

NP_066292.2

NCBI GenBank Nucleotide #

NM_021012.4

UniProt Accession #

Q14500; O43401; Q15756; Q8NG63

Molecular Weight

49,001 Da

NCBI Official Full Name

ATP-sensitive inward rectifier potassium channel 12

NCBI Official Synonym Full Names

potassium inwardly-rectifying channel, subfamily J, member 12

NCBI Official Symbol

KCNJ12

NCBI Official Synonym Symbols

IRK2; hIRK; IRK-2; hIRK1; KCNJN1; Kir2.2; Kir2.2v; kcnj12x; hkir2.2x

NCBI Protein Information

ATP-sensitive inward rectifier potassium channel 12; inward rectifier K(+) channel Kir2.2; inward rectifier K(+) channel Kir2.6; inward rectifier K(+) channel Kir2.2v; potassium channel, inwardly rectifying subfamily J member 12; potassium inwardly-rectifying channel, subfamily J, inhibitor 1

UniProt Protein Name

ATP-sensitive inward rectifier potassium channel 12

UniProt Gene Name

KCNJ12

UniProt Synonym Gene Names

IRK2; KCNJN1; IRK-2

UniProt Entry Name

IRK12_HUMAN

NCBI Description

This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

Uniprot Description

KCNJ12: Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ12 subfamily.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 17p11.2

Cellular Component: integral to plasma membrane; plasma membrane; intrinsic to membrane

Molecular Function: inward rectifier potassium channel activity

Biological Process: synaptic transmission; potassium ion import; muscle contraction; regulation of heart contraction; potassium ion transport; protein homotetramerization

Research Articles on KCNJ12/Kir2.2

1. Unconventional role of the inwardly rectifying potassium channel Kir2.2 as a constitutive activator of RelA in cancer.

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Product Notes

The Mouse KCNJ12/Kir2.2 kcnj12 (Catalog #AAA9306729) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9306729 ELISA Kit recognizes Mouse KCNJ12/Kir2.2. It is sometimes possible for the material contained within the vial of "ATP-sensitive inward rectifier potassium channel 12, KCNJ12/Kir2.2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Mouse ATP-sensitive inward rectifier potassium channel 12, KCNJ12/Kir2.2 ELISA Kit | KCNJ12/Kir2.2 elisa kit