Rat Alpha-1-macroglobulin, Alpha-1-M ELISA Kit | Alpha-1-M elisa kit
Rat Alpha-1-macroglobulin, Alpha-1-M ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
plasma protease inhibitor [RGD, Feb 2006]
Uniprot Description
Function: Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase
By similarity. UniProtKB P01023
Subunit structure: Homotetramer; disulfide-linked
By similarity. UniProtKB P01023
Subcellular location: Secreted Ref.1.
Tissue specificity: Widely expressed. Highest level in ovary, testis, uterus and prostate. Protein found in plasma. Ref.1
Sequence similarities: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. [View classification]
Research Articles on Alpha-1-M
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Product Notes
The Rat Alpha-1-M a1m (Catalog #AAA9306259) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9306259 ELISA Kit recognizes Rat Alpha-1-M. It is sometimes possible for the material contained within the vial of "Alpha-1-macroglobulin, Alpha-1-M, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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