RPS27 blocking peptide

RPS27 Blocking Peptide (N-Term)

• Gene Names: RPS27; S27; MPS1; MPS-1
• Synonyms: RPS27; RPS27 Blocking Peptide (N-Term); 40S ribosomal protein S27; Metallopan-stimulin 1; MPS-1; MPS1; RPS27 blocking peptide

• Specificity: The synthetic peptide sequence is selected from aa 5-17 of HUMAN RPS27
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 84

• Tissue Location: Expressed in a wide variety of actively proliferating cells and tumor tissues
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 1171014
• NCBI GeneID: 6232
• UniProt Accession #: P42677; Q5T4L6
• Molecular Weight: 9,461 Da
• NCBI Official Full Name: 40S ribosomal protein S27
• NCBI Official Synonym Full Names: ribosomal protein S27
• NCBI Official Symbol: RPS27
• NCBI Official Synonym Symbols: S27; MPS1; MPS-1
• NCBI Protein Information: 40S ribosomal protein S27
• UniProt Protein Name: 40S ribosomal protein S27
• Protein Family: 40S ribosomal protein
• UniProt Gene Name: RPS27
• UniProt Synonym Gene Names: MPS1; MPS-1
• UniProt Entry Name: RS27_HUMAN

NCBI Description

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Uniprot Description

RPS27: a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain that can bind to zinc. The encoded protein has been shown to be able to bind to nucleic acid. It is located in the cytoplasm as a ribosomal component, but it has also been detected in the nucleus. Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Protein type: Translation; Ribosomal

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: cytosol; nucleoplasm; nucleus

Molecular Function: protein binding; structural constituent of ribosome

Biological Process: mRNA catabolic process, nonsense-mediated decay; ribosomal small subunit assembly and maintenance; rRNA processing; sister chromatid cohesion; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription