GNG2 blocking peptide

GNG2 Blocking Peptide (N-Term)

• Synonyms: GNG2; GNG2 Blocking Peptide (N-Term); Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2; G gamma-I; GNG2 blocking peptide

• Specificity: The synthetic peptide sequence is selected from aa 19-32 of HUMAN GNG2
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 71

• Cellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side
• Tissue Location: Expressed in fetal tissues, including testis, adrenal gland, brain, white blood cells and brain
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for GNG2 blocking peptide

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity).

NCBI and Uniprot Product Information

• NCBI GI #: 32699499
• NCBI GeneID: 54331
• UniProt Accession #: P59768; Q5JPE2; Q6P9A9
• Molecular Weight: 7,850 Da
• NCBI Official Full Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
• NCBI Official Synonym Full Names: G protein subunit gamma 2
• NCBI Official Symbol: GNG2
• NCBI Protein Information: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
• UniProt Protein Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
• UniProt Gene Name: GNG2
• UniProt Entry Name: GBG2_HUMAN

NCBI Description

This gene encodes one of the gamma subunits of a guanine nucleotide-binding protein. Such proteins are involved in signaling mechanisms across membranes. Various subunits forms heterodimers which then interact with the different signal molecules. [provided by RefSeq, Aug 2011]

Uniprot Description

G-gamma 2: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Belongs to the G protein gamma family.

Protein type: G protein, heterotrimeric gamma; G protein; G protein, heterotrimeric

Chromosomal Location of Human Ortholog: 14q21

Cellular Component: heterotrimeric G-protein complex; membrane; plasma membrane

Molecular Function: G-protein beta-subunit binding

Biological Process: dopamine receptor, adenylate cyclase activating pathway; platelet activation; protein folding; Wnt receptor signaling pathway, calcium modulating pathway