aplnra blocking peptide
aplnra Blocking Peptide (C-Term)
Gene Names
aplnra; Agtr1; agtrl1; agtrl1a; zgc:152843
Synonyms
aplnra; aplnra Blocking Peptide (C-Term); Apelin receptor A; Angiotensin II receptor-like 1a; Angiotensin receptor-like 1a; G-protein coupled receptor APJ A; agtrl1; agtrl1a; aplnra blocking peptide
Specificity
The synthetic peptide sequence is selected from aa 343-357 of HUMAN aplnra
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
362
Cellular Location
Membrane; Multi-pass membrane protein
Tissue Location
First expressed before epiboly in dorsal precursors. During epiboly, expressed in the enveloping layer, yolk syncytial layer and migrating mesendoderm. During segmentation stages, expressed in epithelial structures such as adaxial cells, border cells of the newly formed somites, developing lens, otic vesicles and venous vasculature
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for aplnra blocking peptide
Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for apela hormone, promoting endoderm and mesendoderm cell migration and regulating the migration of cells fated to become myocardial progenitors, respectively (PubMed:24316148, PubMed:24407481). Acts redundantly with agtrl1b in heart development.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
40,649 Da
NCBI Official Full Name
Apelin receptor A
NCBI Official Synonym Full Names
apelin receptor a
NCBI Official Symbol
aplnra
NCBI Official Synonym Symbols
Agtr1; agtrl1; agtrl1a; zgc:152843
NCBI Protein Information
apelin receptor A
UniProt Protein Name
Apelin receptor A
Protein Family
UniProt Gene Name
aplnra
UniProt Entry Name
APJA_DANRE
Uniprot Description
Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for apela hormone, promoting endoderm and mesendoderm cell migration and regulating the migration of cells fated to become myocardial progenitors, respectively (PubMed:24316148, PubMed:24407481). Acts redundantly with agtrl1b in heart development.
Research Articles on aplnra
Similar Products
Product Notes
The aplnra aplnra (Catalog #AAA9229914) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "aplnra, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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