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STOM blocking peptide

STOM Blocking Peptide (N-term)

Gene Names
STOM; BND7; EPB7; EPB72
Synonyms
STOM; STOM Blocking Peptide (N-term); Erythrocyte band 7 integral membrane protein; Protein 72b; Stomatin; BND7; EPB72; STOM blocking peptide
Ordering
Specificity
The synthetic peptide sequence is selected from aa 2-16 of HUMAN STOM
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
288
Cellular Location
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Lipid-anchor; Cytoplasmic side Melanosome. Cytoplasmic vesicle. Note: Exposed on the cytoplasmic surface of the membrane. Associated with lipid rafts Concentrates preferentially in plasma membrane protrusions and in a juxta-nuclear region which may represent Golgi-derived vesicles Colocalizes with actin. Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Tissue Location
Detected in erythrocytes (at protein level). Widely expressed.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for STOM blocking peptide
Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
13,475 Da
NCBI Official Full Name
Erythrocyte band 7 integral membrane protein
NCBI Official Synonym Full Names
stomatin
NCBI Official Symbol
STOM
NCBI Official Synonym Symbols
BND7; EPB7; EPB72
NCBI Protein Information
erythrocyte band 7 integral membrane protein
UniProt Protein Name
Erythrocyte band 7 integral membrane protein
Protein Family
UniProt Gene Name
STOM
UniProt Synonym Gene Names
BND7; EPB72
UniProt Entry Name
STOM_HUMAN

NCBI Description

This gene encodes a member of a highly conserved family of integral membrane proteins. The encoded protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of the encoded protein is associated with hereditary stomatocytosis, a form of hemolytic anemia. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Uniprot Description

stomatin: Thought to regulate cation conductance. May regulate ASIC2 and ASIC3 gating. Belongs to the band 7/mec-2 family.

Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold; Membrane protein, integral

Chromosomal Location of Human Ortholog: 9q34.1

Cellular Component: cytoplasm; cytoskeleton; endoplasmic reticulum; extracellular space; integral to plasma membrane; lipid raft; membrane; mitochondrion; vesicle

Molecular Function: protein binding

Biological Process: positive regulation of defense response to virus by host; protein homooligomerization

Disease: Overhydrated Hereditary Stomatocytosis

Research Articles on STOM

Similar Products

Product Notes

The STOM stom (Catalog #AAA9229362) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "STOM, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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