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Guanylyl Cyclase beta 1 (GUCY1B3) Blocking Peptide | GUCY1B3 blocking peptide

Guanylyl Cyclase beta 1 (GUCY1B3) Antibody (C-term) Blocking peptide

Gene Names
GUCY1B3; GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B1; GC-S-beta-1
Synonyms
Guanylyl Cyclase beta 1 (GUCY1B3); Guanylyl Cyclase beta 1 (GUCY1B3) Antibody (C-term) Blocking peptide; Guanylate cyclase soluble subunit beta-1; GCS-beta-1; Guanylate cyclase soluble subunit beta-3; GCS-beta-3; Soluble guanylate cyclase small subunit; GUCY1B3; GUC1B3; GUCSB3; GUCY1B1; GUCY1B3 blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human GUCY1B3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
Sequence Length
619
Cellular Location
Cytoplasm.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
68,165 Da
NCBI Official Full Name
guanylate cyclase soluble subunit beta-1 isoform 2
NCBI Official Synonym Full Names
guanylate cyclase 1 soluble subunit beta
NCBI Official Symbol
GUCY1B3
NCBI Official Synonym Symbols
GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B1; GC-S-beta-1
NCBI Protein Information
guanylate cyclase soluble subunit beta-1
UniProt Protein Name
Guanylate cyclase soluble subunit beta-1
Protein Family
UniProt Gene Name
GUCY1B3
UniProt Synonym Gene Names
GUC1B3; GUCSB3; GUCY1B1; GCS-beta-3
UniProt Entry Name
GCYB1_HUMAN

NCBI Description

This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Uniprot Description

GUCY1B3: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Heterodimer of an alpha and a beta chain. 2 isoforms of the human protein are produced by alternative splicing

Protein type: Lyase; Guanylyl cyclase; Nucleotide Metabolism - purine; Receptor, misc.; EC 4.6.1.2

Chromosomal Location of Human Ortholog: 4q31.3-q33

Cellular Component: cytoplasm; guanylate cyclase complex, soluble; intracellular membrane-bound organelle; plasma membrane

Molecular Function: adenylate cyclase activity; guanylate cyclase activity; heme binding; protein binding; receptor activity

Biological Process: blood circulation; cGMP biosynthetic process; nitric oxide mediated signal transduction

Research Articles on GUCY1B3

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Product Notes

The GUCY1B3 gucy1b3 (Catalog #AAA9227613) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Guanylyl Cyclase beta 1 (GUCY1B3), Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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