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ALDH9A1 blocking peptide

ALDH9A1 Antibody (C-term) Blocking Peptide

Gene Names
ALDH9A1; E3; ALDH4; ALDH7; ALDH9; TMABADH
Synonyms
ALDH9A1; ALDH9A1 Antibody (C-term) Blocking Peptide; 4-trimethylaminobutyraldehyde dehydrogenase; TMABADH; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; Gamma-aminobutyraldehyde dehydrogenase; R-aminobutyraldehyde dehydrogenase; ALDH4; ALDH7; ALDH9; ALDH9A1 blocking peptide
Ordering
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of human ALDH9A1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
494
Cellular Location
Cytoplasm.
Tissue Location
High expression in adult liver, skeletal muscle, and kidney. Low levels in heart, pancreas, lung and brain Expressed in all regions of the brain. Expression levels are variable in the different brain areas, with the highest levels in the spinal cord and the lowest in the occipital pole
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for ALDH9A1 blocking peptide
Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
223
UniProt Accession #
Molecular Weight
46,455 Da
NCBI Official Full Name
4-trimethylaminobutyraldehyde dehydrogenase
NCBI Official Synonym Full Names
aldehyde dehydrogenase 9 family member A1
NCBI Official Symbol
ALDH9A1
NCBI Official Synonym Symbols
E3; ALDH4; ALDH7; ALDH9; TMABADH
NCBI Protein Information
4-trimethylaminobutyraldehyde dehydrogenase
UniProt Protein Name
4-trimethylaminobutyraldehyde dehydrogenase
UniProt Gene Name
ALDH9A1
UniProt Synonym Gene Names
ALDH4; ALDH7; ALDH9; TMABADH
UniProt Entry Name
AL9A1_HUMAN

NCBI Description

This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits. [provided by RefSeq, Jul 2008]

Uniprot Description

ALDH9A1: Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction. Belongs to the aldehyde dehydrogenase family.

Protein type: Amino Acid Metabolism - histidine; Amino Acid Metabolism - arginine and proline; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pyruvate; Lipid Metabolism - fatty acid; Amino Acid Metabolism - tryptophan; Oxidoreductase; Other Amino Acids Metabolism - beta-alanine; EC 1.2.1.47; Amino Acid Metabolism - lysine degradation; Carbohydrate Metabolism - propanoate; Secondary Metabolites Metabolism - limonene and pinene degradation; Carbohydrate Metabolism - butanoate; EC 1.2.1.3; Mitochondrial; Carbohydrate Metabolism - ascorbate and aldarate; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Lipid Metabolism - glycerolipid

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: cytoplasm; cytosol

Molecular Function: 3-chloroallyl aldehyde dehydrogenase activity; 4-trimethylammoniobutyraldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; aminobutyraldehyde dehydrogenase activity

Biological Process: aldehyde metabolic process; carnitine biosynthetic process; hormone metabolic process; neurotransmitter biosynthetic process

Research Articles on ALDH9A1

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Product Notes

The ALDH9A1 aldh9a1 (Catalog #AAA9227319) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ALDH9A1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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