MS4A3 blocking peptide

MS4A3 Antibody (Center) Blocking Peptide

• Gene Names: MS4A3; HTM4; CD20L
• Synonyms: MS4A3; MS4A3 Antibody (Center) Blocking Peptide; Membrane-spanning 4-domains subfamily A member 3; CD20 antigen-like protein; Hematopoietic-specific transmembrane protein 4; HTm4; CD20L; HTM4; MS4A3 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 214

• Cellular Location: Endomembrane system; Multi- pass membrane protein. Cytoplasm, perinuclear region. Note: Located in the perinuclear area
• Tissue Location: Expressed specifically in hematopoietic cells and tissues
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for MS4A3 blocking peptide

Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin- dependent kinase 2 (CDK2) through its direct binding to cyclin- dependent kinase inhibitor 3 (CDKN3/KAP).

NCBI and Uniprot Product Information

• NCBI GI #: 29611825
• NCBI GeneID: 932
• UniProt Accession #: Q96HJ5; Q8NHW2; A8MTP8
• Molecular Weight: 9,625 Da
• NCBI Official Full Name: Membrane-spanning 4-domains subfamily A member 3
• NCBI Official Synonym Full Names: membrane spanning 4-domains A3
• NCBI Official Symbol: MS4A3
• NCBI Official Synonym Symbols: HTM4; CD20L
• NCBI Protein Information: membrane-spanning 4-domains subfamily A member 3
• UniProt Protein Name: Membrane-spanning 4-domains subfamily A member 3
• Protein Family: Membrane-spanning 4-domains subfamily
• UniProt Gene Name: MS4A3
• UniProt Synonym Gene Names: CD20L; HTM4; HTm4
• UniProt Entry Name: MS4A3_HUMAN

NCBI Description

This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes. The gene encoding this protein is localized to 11q12, among a cluster of related family members. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]

Uniprot Description

MS4A3: Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin- dependent kinase 2 (CDK2) through its direct binding to cyclin- dependent kinase inhibitor 3 (CDKN3/KAP). Belongs to the MS4A family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q12.1

Molecular Function: protein binding