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MSC blocking peptide

MSC Antibody (C-term) Blocking Peptide

Gene Names
MSC; ABF1; MYOR; ABF-1; bHLHa22
Synonyms
MSC; MSC Antibody (C-term) Blocking Peptide; Musculin; Activated B-cell factor 1; ABF-1; Class A basic helix-loop-helix protein 22; bHLHa22; ABF1; BHLHA22; MSC blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
206
Cellular Location
Nucleus.
Tissue Location
Expressed in lymphoid tissues, B-cell lines and activated B-cells
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for MSC blocking peptide
Transcription repressor capable of inhibiting the transactivation capability of TCF3/E47. May play a role in regulating antigen-dependent B-cell differentiation.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
22,068 Da
NCBI Official Full Name
Musculin
NCBI Official Synonym Full Names
musculin
NCBI Official Symbol
MSC
NCBI Official Synonym Symbols
ABF1; MYOR; ABF-1; bHLHa22
NCBI Protein Information
musculin
UniProt Protein Name
Musculin
Protein Family
UniProt Gene Name
MSC
UniProt Synonym Gene Names
ABF1; BHLHA22; ABF-1; bHLHa22
UniProt Entry Name
MUSC_HUMAN

NCBI Description

The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq, Jul 2008]

Uniprot Description

MSC: Transcription repressor capable of inhibiting the transactivation capability of TCF3/E47. May play a role in regulating antigen-dependent B-cell differentiation.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 8q21

Cellular Component: nucleoplasm; nucleus

Molecular Function: transcription corepressor activity; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter

Research Articles on MSC

Similar Products

Product Notes

The MSC msc (Catalog #AAA9222955) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MSC, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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