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ICA1 blocking peptide

ICA1 Antibody (N-term) Blocking Peptide

Gene Names
ICA1; ICA69; ICAp69
Synonyms
ICA1; ICA1 Antibody (N-term) Blocking Peptide; Islet cell autoantigen 1; 69 kDa islet cell autoantigen; ICA69; Islet cell autoantigen p69; ICAp69; p69; ICA1 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
483
Cellular Location
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Note: Predominantly cytosolic. Also exists as a membrane-bound form which has been found associated with synaptic vesicles and also with the Golgi complex and immature secretory granules
Tissue Location
Expressed abundantly in pancreas, heart and brain with low levels of expression in lung, kidney, liver and thyroid
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for ICA1 blocking peptide
May play a role in neurotransmitter secretion.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
54,558 Da
NCBI Official Full Name
Islet cell autoantigen 1
NCBI Official Synonym Full Names
islet cell autoantigen 1
NCBI Official Symbol
ICA1
NCBI Official Synonym Symbols
ICA69; ICAp69
NCBI Protein Information
islet cell autoantigen 1
UniProt Protein Name
Islet cell autoantigen 1
Protein Family
UniProt Gene Name
ICA1
UniProt Synonym Gene Names
ICA69; ICAp69; p69
UniProt Entry Name
ICA69_HUMAN

NCBI Description

This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]

Uniprot Description

ICA1: May play a role in neurotransmitter secretion.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 7p22

Cellular Component: cytoplasm; cytosol; Golgi apparatus; Golgi membrane; secretory granule membrane; synaptic vesicle membrane

Molecular Function: protein binding

Research Articles on ICA1

Similar Products

Product Notes

The ICA1 ica1 (Catalog #AAA9222016) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ICA1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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