TIMM23 blocking peptide

TIMM23 Antibody (C-term) Blocking peptide

• Gene Names: TIMM23; TIM23
• Synonyms: TIMM23; TIMM23 Antibody (C-term) Blocking peptide; Mitochondrial import inner membrane translocase subunit Tim23; TIM23; TIMM23 blocking peptide

• Specificity: The synthetic peptide sequence used to generate the antibody was selected from the C-term region of TIMM23. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 209

• Cellular Location: Mitochondrion inner membrane; Multi-pass membrane protein
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for TIMM23 blocking peptide

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.

NCBI and Uniprot Product Information

• NCBI GI #: 18201964
• NCBI GeneID: 100287932
• UniProt Accession #: O14925; Q53FF8; Q5T1E6; Q6P5S5
• Molecular Weight: 21,943 Da
• NCBI Official Full Name: Mitochondrial import inner membrane translocase subunit Tim23
• NCBI Official Synonym Full Names: translocase of inner mitochondrial membrane 23
• NCBI Official Symbol: TIMM23
• NCBI Official Synonym Symbols: TIM23
• NCBI Protein Information: mitochondrial import inner membrane translocase subunit Tim23
• UniProt Protein Name: Mitochondrial import inner membrane translocase subunit Tim23
• Protein Family: Mitochondrial import inner membrane translocase
• UniProt Gene Name: TIMM23
• UniProt Synonym Gene Names: TIM23
• UniProt Entry Name: TIM23_HUMAN

NCBI Description

The protein encoded by this gene is part of a complex located in the inner mitochondrial membrane that mediates the transport of transit peptide-containing proteins across the membrane. Multiple transcript variants, one protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jul 2012]

Uniprot Description

TIMM23: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Belongs to the Tim17/Tim22/Tim23 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Mitochondrial

Chromosomal Location of Human Ortholog: 10q11.23

Cellular Component: integral to mitochondrial inner membrane; mitochondrial inner membrane; mitochondrial inner membrane presequence translocase complex; mitochondrial intermembrane space; mitochondrion

Molecular Function: protein binding; protein channel activity

Biological Process: protein import into mitochondrial matrix; protein targeting to mitochondrion