NRBP1 blocking peptide

NRBP1 Antibody (N-term) Blocking peptide

• Gene Names: NRBP1; MADM; NRBP; BCON3; MUDPNP
• Synonyms: NRBP1; NRBP1 Antibody (N-term) Blocking peptide; Nuclear receptor-binding protein; BCON3; NRBP; NRBP1 blocking peptide

• Specificity: The synthetic peptide sequence used to generate the antibody was selected from the N-term region of NRBP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 535

• Cellular Location: Cytoplasm, cell cortex. Endomembrane system. Cell projection, lamellipodium. Note: Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia
• Tissue Location: Ubiquitously expressed in all tissues examined with high levels in the testis.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for NRBP1 blocking peptide

May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.

NCBI and Uniprot Product Information

• NCBI GI #: 74761962
• NCBI GeneID: 29959
• UniProt Accession #: Q9UHY1; Q53FZ5; Q96SU3; B3KV40; D6W558
• Molecular Weight: 59,845 Da
• NCBI Official Full Name: Nuclear receptor-binding protein
• NCBI Official Synonym Full Names: nuclear receptor binding protein 1
• NCBI Official Symbol: NRBP1
• NCBI Official Synonym Symbols: MADM; NRBP; BCON3; MUDPNP
• NCBI Protein Information: nuclear receptor-binding protein
• UniProt Protein Name: Nuclear receptor-binding protein
• Protein Family: Nuclear receptor-binding protein
• UniProt Gene Name: NRBP1
• UniProt Entry Name: NRBP_HUMAN

Uniprot Description

NRBP1: May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Protein type: Protein kinase, Other; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Other group; NRBP family

Chromosomal Location of Human Ortholog: 2p23

Cellular Component: cytosol; endomembrane system; nucleoplasm

Molecular Function: protein binding; protein homodimerization activity; protein serine/threonine kinase activity

Biological Process: ER to Golgi vesicle-mediated transport; protein amino acid phosphorylation; transcription initiation from RNA polymerase II promoter